Japan Certified Health Food Association日本語 / 中文
JHFC Association for Japan Health Food Certified
Home / Consumer Verification Guides / Checking anti-fatigue claims

What Supplements Help with Late Nights and Fatigue? A 2026 Guide to Checking Anti-Fatigue Claims

JHFC consumer verification guide Published: November 6, 2026

This guide covers information verification methods only. It does not evaluate the efficacy of any ingredient and does not recommend, rank or certify any specific product.

People who often stay up late, feel tired and low on energy, and are thinking about buying supplements tend to ask three questions: what do you recommend, is NMN useful for younger people, and which product is better. This association does not list brands and does not comment on the effects of any ingredient. This guide covers one thing only: how to check whether claims such as "relieves fatigue," "refreshing," or "anti-fatigue" on a product have any basis. The conclusion first: if fatigue and low energy are long-term, see a doctor first to find the cause before considering supplements.

Rule out medical causes first, then learn to check claims

If you have long-term fatigue or low energy, see a doctor first to find the cause. Supplements are not medicines and are not a substitute for medical care. If you take medication, have a chronic illness, are pregnant, or are breastfeeding, consult a doctor or pharmacist before buying.

When buying a product marketed for "relieving fatigue," the first thing to check is not the advertising but what category the product falls into. On mainland China, health foods carry the "blue hat" health food logo plus a registration number or filing number, which you can check in the special food information database of China's State Administration for Market Regulation (SAMR). The permitted health function list includes "relieving physical fatigue." To see whether a specific product is approved for this function, check the "health function" field on the blue hat approval certificate or filing certificate. A product without the blue hat logo is an ordinary food and must not claim health functions.

Products from Japan need to be looked at separately. Foods with Function Claims (FFC) are filed with the Consumer Affairs Agency (CAA) by notification (届出); this is a filing, not an approval. The specific functional statement is whatever is stated in the notification. You can search by product name or notification number in the CAA's notification search for Foods with Function Claims (機能性表示食品の届出情報検索) on the CAA website. Foods for Specified Health Uses (FOSHU) are individually approved by the CAA. Japan has no legal category called "health foods." Products sold as "health foods" are legally just foods, and they cannot make drug-like treatment claims.

Words like "refreshing," "anti-fatigue," or "restores energy" on an ordinary food label or an online store page do not mean the product has a health function. If a product has no blue hat logo and does not appear in the Japanese FFC notification database, but the marketing repeatedly uses these terms, go back to the previous question: what category is it? For products containing caffeine or similar ingredients, also check whether the ingredient list states caffeine and whether the precautions include unsuitable groups and reminders about the recommended daily intake. A product that says only "natural energy boost" without listing ingredients and precautions is giving incomplete information.

Verification checklist

Use the table below as a checklist.

Item to checkWhere to lookWhat adequate information looks likeWarning signs
Mainland China health food functionRegistration or filing number next to the blue hat logo; the special food information databaseThe "health function" field in the search result lists a function from the permitted list, such as "relieving physical fatigue," and matches the product claimNo blue hat logo but health functions are advertised; page only uses terms like "refreshing" or "anti-fatigue" and no approval or filing record can be found
Japanese Foods with Function ClaimsThe CAA's notification search for Foods with Function Claims (機能性表示食品の届出情報検索)You can find the notification number, product name, functional statement, and supporting materialsProduct only states "imported from Japan" or "made in Japan" with no notification number; treats Foods for Specified Health Uses and Foods with Function Claims as the same thing
Claims on ordinary Japanese "health foods"Packaging, online store product pageDoes not make drug-like treatment claims, does not exaggerate or misleadWords such as "treat," "cure," or "eliminate the root cause" appear
Telling ordinary food from health foodWhether the label has the blue hat logoOnly products with the blue hat logo are health foods; products without it are ordinary foods and must not claim health functionsOrdinary food label or product page says "restores energy" or "relieves physical fatigue"
Import methodChinese label and statement of import methodPrepackaged food imported through general trade has a Chinese label; cross-border e-commerce retail imports are treated as personal-use items, may have no Chinese label, and the platform must provide a risk noticeProduct page does not state the import method; cross-border goods are resold in large quantities
Online store operatorBusiness license and other information displayed on the store home page or product pageThe operator name matches the license, and after-sales service and invoices can be checkedNo business license shown; operator name does not match the payee
Products containing caffeine or similar ingredientsIngredient list and precautions on the labelStates whether the product contains caffeine, unsuitable groups, and reminders about the recommended daily intakeOnly says "refreshing"; does not state caffeine content and has no precautions
NMN finished-product contentProduct label and test report (certificate of analysis)States how many milligrams of NMN each capsule/tablet or daily serving contains; test report includes lot number, test method, and whether the sample is raw material or finished productOnly gives "raw material purity" with no finished-product content; uses purity to replace finished-product content

Late nights and NMN products: only look at whether the label is clear

This guide does not evaluate whether NMN is useful for younger people who often stay up late. Whether NMN can be used as an ordinary food ingredient in mainland China depends on the new food ingredient announcements published by China's National Health Commission (NHC). Readers can check those announcements themselves; do not decide on your own.

If you do buy an NMN product, what you can check is the label and the test report (certificate of analysis). NMN (nicotinamide mononucleotide), NR (nicotinamide riboside), niacin, and nicotinamide are all called NAD+ precursors in biochemistry, but they are different chemical substances. They should be listed separately on the label, not lumped together. NMN raw material purity usually refers to test results for the raw material itself and is not the same as the amount per capsule/tablet in the finished product. For finished products, look at how many milligrams each capsule/tablet or daily serving contains. Purity is usually measured by high-performance liquid chromatography (HPLC) or similar methods. The test report should state the test method, whether the sample is raw material or finished product, and the lot number. Besides purity, raw material testing may also include related substances, heavy metals, and microorganisms.

Common misconceptions

Related JHFC standards

Scope of this guide

This guide only explains how to verify information. It does not evaluate the effects of any ingredient or product, and it does not recommend or certify any specific product. For questions like "what can I take to relieve fatigue?", this association's answer is: first ask a doctor to find the cause of long-term fatigue, then use the checklist above to check the product's claims. If you take medication, have a chronic illness, are pregnant, or are breastfeeding, consult a doctor or pharmacist before buying.

Other guides: Checking NMN rankings and reviews · 8 checks before buying anti-aging supplements · NMN checklist for older adults · Checklist for gifting supplements to parents · Checking telomere claims · Label checks for NAD+ supplements · Checking imported and premium products · Choosing NMN and avoiding pitfalls · Working out NMN value per milligram · Checking NMN purity claims · Checking NMN dosage-form claims · Label checks for NMN and NMNH · Checking cross-border NMN purchases · Comparing domestic and imported NMN · Label checks for fish oil and DHA · Label checks for coenzyme Q10 · Checking online stores · Reading Japanese supplement labels · Checking nattokinase labels · Checking lutein labels · Checking glucosamine and chondroitin labels · Checking collagen peptide labels · Checking strains and counts · Checking red yeast rice products · Vitamin units and multivitamin labels · Complaints and keeping evidence · Checking placenta extract labels · Turmeric and curcumin labels · Checking ornithine labels · Aojiru ingredients and ratios · Checking propolis labels · Isoflavone and equol labels · Oral hyaluronic acid and ceramide · Checking maca labels · Checking saw palmetto labels